Schema of cystathione b-synthase-mediated activation of HIF and PHD2... | Download Scientific Diagram
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates | eLife
Small-molecule inhibitors of HIF-PHD2: a valid strategy to renal anemia treatment in clinical therapy - MedChemComm (RSC Publishing)
IOX4 is a Highly Selective PHD2 Inhibitor - Immune System Research
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases | Nature Communications
4 Structural overview of the HIF prolyl hydroxylase PHD2. Views from... | Download Scientific Diagram
Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells
A) The PHD2:HIF pathway. (Left) Under normoxic conditions, PHD2... | Download Scientific Diagram
Regulation of HIF pathway. Under normoxia, PHDs (PHD1, PHD2 and PHD3)... | Download Scientific Diagram
Role and regulation of prolyl hydroxylase domain proteins | Cell Death & Differentiation
Frontiers | Possible Role of PHD Inhibitors as Hypoxia-Mimicking Agents in the Maintenance of Neural Stem Cells' Self-Renewal Properties
Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation | Scientific Reports
The novel prolyl hydroxylase-2 inhibitor caffeic acid upregulates hypoxia inducible factor and protects against hypoxia - ScienceDirect
A small-molecule probe for monitoring binding to prolyl hydroxylase domain 2 by fluorescence polarisation - Chemical Communications (RSC Publishing) DOI:10.1039/D0CC06353C
The PHD2:HIF-2α:VHL pathway and EPO gene regulation. Under normoxic... | Download Scientific Diagram
Regulation of HIF-1α by FIH and PHD2 | Download Scientific Diagram
Molecules | Free Full-Text | Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications
The Hypoxia-Inducible Factor Pathway (HIF) | Haase Lab
The ribosomal chaperone NACA recruits PHD2 to cotranslationally modify HIF‐α | The EMBO Journal
The HIF-1 pathway. In normoxia, the oxygen-sensing hydroxylases PHD1,... | Download Scientific Diagram
Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α | Scientific Reports
A) The PHD2:HIF pathway. (Left) Under normoxic conditions, PHD2... | Download Scientific Diagram
Regulation of glycolysis by PHD2 is HIF-1α-independent. (A)... | Download Scientific Diagram
IJMS | Free Full-Text | Structural Characterization of Hypoxia Inducible Factor α—Prolyl Hydroxylase Domain 2 Interaction through MD Simulations
IJMS | Free Full-Text | Structural Characterization of Hypoxia Inducible Factor α—Prolyl Hydroxylase Domain 2 Interaction through MD Simulations
